Typhoid
Diagnosis - TYPHIDOT
Dot EIA for the rapid detection of specific IgM and
IgG antibodies against a specific antigen for Salmonella
typhi.
FEATURES
• Rapid
• Simple, easy & convenient
• 10 µl of serum is needed
• High sensitivity, specificity, positive & negative
predictive values (>95%)
• Detects both IgG & IgM separately
• Cost effective
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PROCEDURES
FOR TYPHIDOT |
BENEFITS
• Early & definitive diagnosis of typhoid
fever
• No special equipment is needed
• Results are very easy to read & interpret
• Can diagnose typhoid with a single serum specimen
• No sample preparation
• Low volume used
• Higher than current serological tests
• Increases confidence level
• Indicates the stages of typhoid infection
• Early definitive treatment, reduces investigations
and hospital stay
PERFORMANCE
CHARACTERISTICS
Method : Enzyme Immunoassay
Detection : Specific IgM and IgG antibodies against specific Salmonella typhi
antigens in human serum
Specimen : Serum
Specimen volume : 10 µl
Shelf life : 12 months
Assay time : 1 hour |
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TEST PERFORMANCE
Sensitivity
Specificity
Negative Predictive Value
Positive Predictive Value |
---->95% |
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ORDERING
INFORMATION
Typhidot 1 Hour (28T) : MBDr/T01/28T
Typhidot 1 Hour (56T) : MBDr/T01/56T
Typhidot M : MBDr/T02/30T
Typhidot 3 Hours : MBDr/T03/28T
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INTERPRETATION OF RESULTS
IgM positive only Acute typhoid fever
IgM & IgG positive Acute typhoid fever
(in the middle stage of infection)
IgG positive Implications for the presence of
IgG antibodies include relapse or
reinfection or previous infection
(in which case current fever may
not be due to typhoid). In such cases,
confirmation can be obtained from
TYPHIDOT-M results MBDr/T02/307.
IgM & IgG negative Probably not typhoid |
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